Post by account_disabled on Oct 26, 2023 4:02:56 GMT -6
This article aims to discuss the different resistance mechanisms, the techniques currently available for identifying microorganisms isolated from MRSA, the application of these strain discrimination methods and their use in epidemiological investigation as well as infection control practices. The approach requires considering that Staphylococcus aureus is implicated in a variety of infections ranging from soft tissue infections to bone tissue infections, pneumonia, and endocarditis. Both community-acquired and hospital-acquired infections related to Staphylococcus aureus have increased over the past two decades and this increase in incidence has been accompanied by an increase in strains resistant to antibiotics, in particular methicillin.
The latter are called methicillin-resistant Staphylococcus aureus (MRSA). Several resistance mechanisms have been described. Identification of MRSA is essential to understand epidemiological trends and initiate infection control strategies. Phenotype-based methods are easy to perform and interpret, in addition to having a relatively low cost, but they are less discriminatory. Genotypic methods, which have the advantage of being more discriminatory, are more expensive and technically demanding. However, there is no consensus on europe mobile number list the best identification method. In relation to these methods, we can mention pulsed-field gel electrophoresis (PFGE), which continues to be the gold standard for strain characterization, and DNA sequencing methods, which require technical knowledge and increase in cost. The reported data were obtained through literature reviews during the second half of 2019 and the first half of 2020, through research in books and scientific journals, and on search engines: www.scielo.com.br and www.pubmed .com.br. Keywords: Staphylococcus aureus, MRSA, methicillin. INTRODUCTION This article aims to discuss the different resistance mechanisms, the techniques currently available for identifying microorganisms isolated from MRSA, the application of these strain discrimination methods and their use in epidemiological investigation as well as infection control practices.
In this sense, it is important to bear in mind that Staphylococcus aureus causes a variety of suppurative infections (with the formation of pus) and the release of toxins in humans. They are agents that cause superficial skin lesions such as boils, more serious infections such as pneumonia, phlebitis, meningitis, urinary tract infections and deep infections such as osteomyelitis and endocarditis. S. aureus is one of the main causes of hospital-acquired (nosocomial) infection of surgical wounds.
The latter are called methicillin-resistant Staphylococcus aureus (MRSA). Several resistance mechanisms have been described. Identification of MRSA is essential to understand epidemiological trends and initiate infection control strategies. Phenotype-based methods are easy to perform and interpret, in addition to having a relatively low cost, but they are less discriminatory. Genotypic methods, which have the advantage of being more discriminatory, are more expensive and technically demanding. However, there is no consensus on europe mobile number list the best identification method. In relation to these methods, we can mention pulsed-field gel electrophoresis (PFGE), which continues to be the gold standard for strain characterization, and DNA sequencing methods, which require technical knowledge and increase in cost. The reported data were obtained through literature reviews during the second half of 2019 and the first half of 2020, through research in books and scientific journals, and on search engines: www.scielo.com.br and www.pubmed .com.br. Keywords: Staphylococcus aureus, MRSA, methicillin. INTRODUCTION This article aims to discuss the different resistance mechanisms, the techniques currently available for identifying microorganisms isolated from MRSA, the application of these strain discrimination methods and their use in epidemiological investigation as well as infection control practices.
In this sense, it is important to bear in mind that Staphylococcus aureus causes a variety of suppurative infections (with the formation of pus) and the release of toxins in humans. They are agents that cause superficial skin lesions such as boils, more serious infections such as pneumonia, phlebitis, meningitis, urinary tract infections and deep infections such as osteomyelitis and endocarditis. S. aureus is one of the main causes of hospital-acquired (nosocomial) infection of surgical wounds.